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Amelioration of mitochondrial dysfunction in heart failure t

发布时间:2021-01-14 08:50
  OBJECTIVE To determine the functional role of hydrogen sulfide(H2S) in protecting against mitochondrial dysfunction in heart failure through the inhibition of Ca2+/calmodulin-dependent protein kinaseⅡ(Ca MKⅡ) using wild type and CSE knockout mouse models.METHODS Continuous subcutaneous injection isoprenaline(7.5 mg·kg-1 per day),once a day for 4 weeks to induce heart failure in male C57BL/6(6-8 weeks old) mice and CSE-/-mice.150 μmol·L-1 H2O... 

【文章来源】:中国药理学与毒理学杂志. 2017,31(10)北大核心

【文章页数】:1 页


本文编号:2976603

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